# Readings

## Required Textbooks

Weiss, Thomas F. Cellular Biophysics: Transport. Vol. 1. Cambridge, MA: MIT Press, 1996. ISBN: 9780262231831.

———. Cellular Biophysics: Electrical Properties. Vol. 2. Cambridge, MA: MIT Press, 1996. ISBN: 9780262231848.

Course readings.
ses # | Topics | READINGS
--- | --- | ---
L1 | Introduction to Cellular Transport |
R1 | Review of Differential Equations |
L2 | Macroscopic and Microscopic Laws of Diffusion | Weiss. Volume 1: 3.1-3.1.3, 3.2-3.2.2.
L3 | Continuity and Diffusion Equations | Weiss. Volume 1: 3.1.4-3.1.5, 3.5-3.5.2.1.
R2 | Diffusion |
L4 | Diffusion in Cells: Models | Weiss. Volume 1: 3.6-3.6.1.2, 3.7-3.7.2.
R3 | Diffusion (cont.) |
L5 | Diffusion in Cells: Experiments | Weiss. Volume 1: 3.8-3.8.5.
L6 | Osmosis: van Hoff's Law | Weiss. Volume 1: 4.1-4.3.2.3, 4.4-4.5.1.2.
R4 | Diffusion and Osmosis |
L7 | Osmosis in Cells: Equilibrium | Weiss. Volume 1: 4.7-4.7.1.2.
R5 | Osmosis |
L8 | Chemical Transport | Weiss. Volume 1: 4.7.2-Fig. 4.26 (p. 230), Fig. 4.28, 4.8.2-4.8.3, 6.1-6.2.1.4.
L9 | Four-State Symmetric Carrier Model | Weiss. Volume 1: 6.4-6.4.1.4.
R6 | Osmosis and Carrier Mediated Transport |
L10 | Carrier Models | Weiss. Volume 1: 6.4.2-6.4.3, 6.6-6.7.4.
R7 | 4-State Model |
L11 | Glucose Regulation | Weiss. Volume 1: 7.2.1, 7.2.3, 7.2.4.1, 7.4.
L12 | Ion Transport: Nernst-Planck Equation |
R8 | Carrier Models |
L13 | Writing a Laboratory Report |
| Exam 1 |
L14 | Ion Transport: Models |
R9 | Ions |
L15 | Ion Transport Models (cont.) | Weiss. Volume 1: 7.5.
R10 | Ions (cont.) |
L16 | Active Transport | Weiss. Volume 1: 7.5.
L17 | Electrical Properties of Cells | Weiss. Volume 2: Chapter 1.
| Writing Clinic |
L18 | Core Conductor Model of Large Cells | Weiss. Volume 2: 2.1-2.4.2.
R11 | Core Conductor |
L19 | Core Conductor | Weiss. Volume 2: 2.4.3-2.5.
L20 | HH: Space Clamp | Weiss. Volume 2: 4.1-4.1.2.3, 4.2-4.2.2.2.
R12 | Core Conductor (cont.) |
L21 | HH: Voltage Clamp | Weiss. Volume 2: 4.2.3-4.2.3.1.
R13 | Core Conductor (cont.) |
L22 | HH: Current Clamp | Weiss. Volume 2: 4.2.3-4.2.3.2.
L23 | Demo: HH Project | Weiss. Volume 2: 4.3.
R14 | HH Elec Classroom |
L24 | HH Project | Weiss. Volume 2: 4.4.8.
| Exam 2 |
L25 | HH: Threshold | Weiss. Volume 2: 4.4.1.
L26 | Cable Model | Weiss. Volume 2: 3.1-3.2.1, 3.3-3.4.2.1.
R15 | HH Elec Classroom (cont.) |
L27 | Cable Model (cont.) |
L28 | Writing an Oral Presentation | Weiss. Volume 2: 3.4.2.4-3.4.3.1, 3.4.3.3-3.5.
L29 | Myelinated Fibers | Weiss. Volume 2: 5.1-5.2.4.4.
R16 | Cable Model |
L30 | Saltatory Conduction | Weiss. Volume 2: 5.3-5.7.
R17 | Saltatory Conduction |
L31 | Patch Clamp | Weiss. Volume 2: 6.1-6.1.1, 6.4-6.4.1.5, 6.2-6.2.2, 6.5-p. 407.
L32 | Ion Channels: 2-State Models | Weiss. Volume 2: 6.5-p. 407.
| HH Dry Runs |
L33 | Ion Channels: 4 Gate Model | Weiss. Volume 2: p. 407-p. 416.
L34 | Ion Channels: Gating Currents | Weiss. Volume 2: 6.3.2-6.3.6.
R18 | Ion Channels |
R19 | Ion Channels (cont.) |
L35 | Ion Channels Multi-State Models | Weiss. Volume 2: 6.6, 6.7.
R20 | Ion Channels (cont.) |
L36 | Breakfast with the Staff |
R21 | Ion Channels (cont.) |
| Final Exam Period |