# Bench to Bedside: Molecularly Targeted Therapies in Blood Disorders and Malignancy

Gleevec (in red) is a drug used to treat chronic myeloid leukemia (CML). It works by inhibiting bcr-abl kinase (in green), the protein that causes CML. (Image courtesy of RCSB Protein Data Bank entry 1IEP.)

### Instructor(s)

Dr. Johan Flygare

Dr. Bill Wong

### MIT Course Number

7.341

### As Taught In

Fall 2009

### Level

Undergraduate

###

Some Description
Instructor(s) | Prof.
As Taught In | Spring 2002
Course Number | 2.24
Level | Undergraduate/Graduate
Features | Lecture Notes, Student Work

## Course Description

Where do new drugs and treatments come from? This class will take you from the test tubes and mice of the laboratory to the treatment of patients with deadly blood disorders. Students will learn how to think as a scientist through discussion of primary research papers describing the discoveries of several novel treatments. Topics such as gene therapy, the potential of drugs based on RNA interference and the reprogramming of somatic cells into stem cells for regenerative medicine will be discussed.

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

## Related Content

## Course Collections

See related courses in the following collections:

### Cross-Disciplinary Lists

- Life Sciences Courses

### Find Courses by Topic

- Cellular and Molecular Medicine
- Biology > Stem Cells
- Biology > Genetics

Johan Flygare, and Bill Wong. 7.341 Bench to Bedside: Molecularly Targeted Therapies in Blood Disorders and Malignancy. Fall 2009. Massachusetts Institute of Technology: MIT OpenCourseWare, https://ocw.mit.edu. License: Creative Commons BY-NC-SA.

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